People grappling with pain often seek sanctuary within opioid pill bottles. Opioids are synthetic pain-management drugs, the most common of which are oxycodone, hydrocodone and fentanyl. Much like their natural opiate counterparts—morphine, opium, codeine and heroin, all of which are derived from poppy seeds—they bind to the opioid receptors in the brain and keep messages of pain from being delivered to the body, removing the sensation of pain for the user and replacing it with a sensation of comfort and bliss.